Mesotherapy involves a series of injections containing minute quantities of vasodilators, nonsteroidal, anti-inflammatory medications, enzymes, nutrients, antibiotics, hormones and calcitonin into the layer of fat under the skin. Mesotherapy was originally developed to treat vascular and lymphatic disorders, however depending upon the substance injected; it is also used to treat chronic pain, alopecia, bone and joint disorders, and psoriasis. A common use for mesotherapy is body contouring, accomplished by treating cellulite, reducing body fat and spot weight loss. A specially designed applicator system with a very fine needle is used to inject the desired drug or injectable underneath the dermal layer of the skin into the subcutaneous adipose fat in the area selected for body contouring.
Some claim a mechanism of action through increased blood flow in the capillary networks as well as increased lymphatic flow throughout the mesoderm. Others indicate that the medications cause shrinkage of fat cells by dissolving fat which is then excreted through the urine and bowels. Immediate or delayed allergic reactions to the injected drugs/solutions, skin infections requiring antibiotics and urticaria-pigmentosa at the injection site are some of the reported side-effects of mesotherapy. It is also known that lecithin can cause inflammation and swelling at the injection site.